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CD4 T cells reactive to an IAPP peptide accumulate in the pancreas and contribute to disease pathogenesis in NOD mice
We previously reported a peptide KS20 from islet amyloid polypeptide (IAPP) to be the target antigen for a highly diabetogenic CD4 T cell clone BDC-5.2.9. In order to track IAPP-reactive T cells in NOD mice and determine how they contribute to the pathogenesis of type 1 diabetes (T1D), we designed a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3815676/ https://ncbi.nlm.nih.gov/pubmed/24043895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301480 |
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