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Pharmacogenetic Trial of a Cannabinoid Agonist Shows Reduced Fasting Colonic Motility in Patients with Non-Constipated Irritable Bowel Syndrome
BACKGROUND: Cannabinoid receptors are located on cholinergic neurons. Genetic variants that affect endocannabinoid metabolism are associated with colonic transit in patients with irritable bowel syndrome with diarrhea (IBS-D). We compared the effects of dronabinol, a non-selective agonist of the can...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3202649/ https://ncbi.nlm.nih.gov/pubmed/21803011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.07.036 |
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