PPARα activation promotes macrophage reverse cholesterol transport through an LXR-dependent pathway

OBJECTIVE: Peroxisome proliferator-activate receptorα (PPARα) activation has been shown in vitro to increase macrophage cholesterol efflux, the initial step in reverse cholesterol transport (RCT). However, it remains unclear whether PPARα activation promotes macrophage RCT in vivo. METHODS AND RESUL...

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Bibliografiset tiedot
Päätekijät: Nakaya, Kazuhiro, Tohyama, Junichiro, Naik, Snehal U, Tanigawa, Hiroyuki, Jaye, Michael, MacPhee, Colin, Billheimer, Jeffrey T, Rader, Daniel J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202300/
https://ncbi.nlm.nih.gov/pubmed/21441141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.225383
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