Overexpression and deletion of phospholipid transfer protein reduce HDL mass and cholesterol efflux capacity but not macrophage reverse cholesterol transport

Phospholipid transfer protein (PLTP) may affect macrophage reverse cholesterol transport (mRCT) through its role in the metabolism of HDL. Ex vivo cholesterol efflux capacity and in vivo mRCT were assessed in PLTP deletion and PLTP overexpression mice. PLTP deletion mice had reduced HDL mass and cho...

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Bibliografische gegevens
Gepubliceerd in:J Lipid Res
Hoofdauteurs: Kuwano, Takashi, Bi, Xin, Cipollari, Eleonora, Yasuda, Tomoyuki, Lagor, William R., Szapary, Hannah J., Tohyama, Junichiro, Millar, John S., Billheimer, Jeffrey T., Lyssenko, Nicholas N., Rader, Daniel J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Biochemistry and Molecular Biology 2017
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392748/
https://ncbi.nlm.nih.gov/pubmed/28137768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M074625
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