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Human paraoxonase 1 overexpression in mice stimulates HDL cholesterol efflux and reverse cholesterol transport

This study was aimed to investigate the effect of human PON1 overexpression in mice on cholesterol efflux and reverse cholesterol transport. PON1 overexpression in PON1-Tg mice induced a significant 3-fold (p<0.0001) increase in plasma paraoxonase activity and a significant ~30% (p<0.0001) inc...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Ikhlef, Souade, Berrougui, Hicham, Kamtchueng Simo, Olivier, Zerif, Echarki, Khalil, Abdelouahed
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344486/
https://ncbi.nlm.nih.gov/pubmed/28278274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173385
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