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Human paraoxonase 1 overexpression in mice stimulates HDL cholesterol efflux and reverse cholesterol transport

This study was aimed to investigate the effect of human PON1 overexpression in mice on cholesterol efflux and reverse cholesterol transport. PON1 overexpression in PON1-Tg mice induced a significant 3-fold (p<0.0001) increase in plasma paraoxonase activity and a significant ~30% (p<0.0001) inc...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Ikhlef, Souade, Berrougui, Hicham, Kamtchueng Simo, Olivier, Zerif, Echarki, Khalil, Abdelouahed
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344486/
https://ncbi.nlm.nih.gov/pubmed/28278274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173385
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