Both the Peroxisome Proliferator‐Activated Receptor δ Agonist, GW0742, and Ezetimibe Promote Reverse Cholesterol Transport in Mice by Reducing Intestinal Reabsorption of HDL‐Derived Cholesterol

Peroxisome proliferator‐activated receptor δ (PPARδ) agonism increases HDL cholesterol and has therefore the potential to stimulate macrophage‐to‐feces reverse cholesterol transport (RCT). To test whether PPAR™ activation promotes RCT in mice, in vivo macrophage RCT was assessed using cholesterol‐lo...

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Detalhes bibliográficos
Main Authors: Briand, François, Naik, Snehal U., Fuki, Ilia, Millar, John S., Macphee, Colin, Walker, Max, Billheimer, Jeffrey, Rothblat, George, Rader, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2009
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823289/
https://ncbi.nlm.nih.gov/pubmed/20169010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2009.00098.x
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