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Molecular sensing by the aptamer domain of the FMN riboswitch: a general model for ligand binding by conformational selection

Understanding the nature of the free state of riboswitch aptamers is important for illuminating common themes in gene regulation by riboswitches. Prior evidence indicated the flavin mononucleotide (FMN)-binding riboswitch aptamer adopted a ‘bound-like’ structure in absence of FMN, suggesting only lo...

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Dettagli Bibliografici
Autori principali: Vicens, Quentin, Mondragón, Estefanía, Batey, Robert T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
RNA
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201879/
https://ncbi.nlm.nih.gov/pubmed/21745821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr565
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