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Molecular sensing by the aptamer domain of the FMN riboswitch: a general model for ligand binding by conformational selection

Understanding the nature of the free state of riboswitch aptamers is important for illuminating common themes in gene regulation by riboswitches. Prior evidence indicated the flavin mononucleotide (FMN)-binding riboswitch aptamer adopted a ‘bound-like’ structure in absence of FMN, suggesting only lo...

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Autors principals: Vicens, Quentin, Mondragón, Estefanía, Batey, Robert T.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
RNA
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201879/
https://ncbi.nlm.nih.gov/pubmed/21745821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr565
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