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Interplay of ‘induced fit’ and preorganization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch

Riboswitches are highly structured elements in the 5′-untranslated regions (5′-UTRs) of messenger RNA that control gene expression by specifically binding to small metabolite molecules. They consist of an aptamer domain responsible for ligand binding and an expression platform. Ligand binding in the...

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Autors principals: Noeske, Jonas, Buck, Janina, Fürtig, Boris, Nasiri, Hamid R., Schwalbe, Harald, Wöhnert, Jens
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2007
Matèries:
RNA
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802621/
https://ncbi.nlm.nih.gov/pubmed/17175531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1094
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