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Interplay of ‘induced fit’ and preorganization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch

Riboswitches are highly structured elements in the 5′-untranslated regions (5′-UTRs) of messenger RNA that control gene expression by specifically binding to small metabolite molecules. They consist of an aptamer domain responsible for ligand binding and an expression platform. Ligand binding in the...

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Autores principales: Noeske, Jonas, Buck, Janina, Fürtig, Boris, Nasiri, Hamid R., Schwalbe, Harald, Wöhnert, Jens
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802621/
https://ncbi.nlm.nih.gov/pubmed/17175531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1094
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