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Influence of ground-state structure and Mg(2+) binding on folding kinetics of the guanine-sensing riboswitch aptamer domain

Riboswitch RNAs fold into complex tertiary structures upon binding to their cognate ligand. Ligand recognition is accomplished by key residues in the binding pocket. In addition, it often crucially depends on the stability of peripheral structural elements. The ligand-bound complex of the guanine-se...

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Bibliografische gegevens
Hoofdauteurs: Buck, Janina, Wacker, Anna, Warkentin, Eberhart, Wöhnert, Jens, Wirmer-Bartoschek, Julia, Schwalbe, Harald
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239184/
https://ncbi.nlm.nih.gov/pubmed/21890900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr664
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