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Influence of ground-state structure and Mg(2+) binding on folding kinetics of the guanine-sensing riboswitch aptamer domain

Riboswitch RNAs fold into complex tertiary structures upon binding to their cognate ligand. Ligand recognition is accomplished by key residues in the binding pocket. In addition, it often crucially depends on the stability of peripheral structural elements. The ligand-bound complex of the guanine-se...

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Détails bibliographiques
Auteurs principaux: Buck, Janina, Wacker, Anna, Warkentin, Eberhart, Wöhnert, Jens, Wirmer-Bartoschek, Julia, Schwalbe, Harald
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239184/
https://ncbi.nlm.nih.gov/pubmed/21890900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr664
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