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Molecular dynamics simulation study of the binding of purine bases to the aptamer domain of the guanine sensing riboswitch

Riboswitches are a novel class of genetic control elements that function through the direct interaction of small metabolite molecules with structured RNA elements. The ligand is bound with high specificity and affinity to its RNA target and induces conformational changes of the RNA's secondary...

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Bibliografski detalji
Glavni autori: Villa, Alessandra, Wöhnert, Jens, Stock, Gerhard
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
RNA
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724292/
https://ncbi.nlm.nih.gov/pubmed/19515936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp486
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