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Influence of ground-state structure and Mg(2+) binding on folding kinetics of the guanine-sensing riboswitch aptamer domain

Riboswitch RNAs fold into complex tertiary structures upon binding to their cognate ligand. Ligand recognition is accomplished by key residues in the binding pocket. In addition, it often crucially depends on the stability of peripheral structural elements. The ligand-bound complex of the guanine-se...

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Bibliografski detalji
Glavni autori: Buck, Janina, Wacker, Anna, Warkentin, Eberhart, Wöhnert, Jens, Wirmer-Bartoschek, Julia, Schwalbe, Harald
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239184/
https://ncbi.nlm.nih.gov/pubmed/21890900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr664
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