Free state conformational sampling of the SAM-I riboswitch aptamer domain

Riboswitches are highly structured elements residing in the 5' untranslated region of messenger RNAs that specifically bind cellular metabolites to alter gene expression. While there are many structures of ligand bound riboswitches that reveal details of bimolecular recognition, their unligande...

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Bibliographic Details
Main Authors: Stoddard, Colby D, Montange, Rebecca K., Hennelly, Scott P., Rambo, Robert P., Sanbonmatsu, Karissa Y., Batey, Robert T.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917978/
https://ncbi.nlm.nih.gov/pubmed/20637415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.04.006
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