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Free state conformational sampling of the SAM-I riboswitch aptamer domain

Riboswitches are highly structured elements residing in the 5' untranslated region of messenger RNAs that specifically bind cellular metabolites to alter gene expression. While there are many structures of ligand bound riboswitches that reveal details of bimolecular recognition, their unligande...

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Autors principals: Stoddard, Colby D, Montange, Rebecca K., Hennelly, Scott P., Rambo, Robert P., Sanbonmatsu, Karissa Y., Batey, Robert T.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917978/
https://ncbi.nlm.nih.gov/pubmed/20637415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.04.006
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