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Specific recognition of apurinic sites in DNA by a tryptophan-containing peptide.

We have used fluorescence spectroscopy to study the binding of lysyltryptophyl-alpha-lysine (Lys-Trp-Lys) to DNA modified by dimethyl sulfate before and after depurination and strand breakage. Quenching of tryptophan fluorescence increased upon association of the peptide with modified DNA as compare...

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Autors principals: Behmoaras, T, Toulme, J J, Helene, C
Format: Artigo
Idioma:Inglês
Publicat: 1981
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC319917/
https://ncbi.nlm.nih.gov/pubmed/6940157
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