Specific recognition of apurinic sites in DNA by a tryptophan-containing peptide.

We have used fluorescence spectroscopy to study the binding of lysyltryptophyl-alpha-lysine (Lys-Trp-Lys) to DNA modified by dimethyl sulfate before and after depurination and strand breakage. Quenching of tryptophan fluorescence increased upon association of the peptide with modified DNA as compare...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Behmoaras, T, Toulme, J J, Helene, C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1981
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319917/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6940157/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.2.926
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