Specific recognition of apurinic sites in DNA by a tryptophan-containing peptide.
We have used fluorescence spectroscopy to study the binding of lysyltryptophyl-alpha-lysine (Lys-Trp-Lys) to DNA modified by dimethyl sulfate before and after depurination and strand breakage. Quenching of tryptophan fluorescence increased upon association of the peptide with modified DNA as compare...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1981
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319917/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6940157/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.2.926 |
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