Specific recognition of apurinic sites in DNA by a tryptophan-containing peptide.

We have used fluorescence spectroscopy to study the binding of lysyltryptophyl-alpha-lysine (Lys-Trp-Lys) to DNA modified by dimethyl sulfate before and after depurination and strand breakage. Quenching of tryptophan fluorescence increased upon association of the peptide with modified DNA as compare...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Behmoaras, T, Toulme, J J, Helene, C
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1981
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319917/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6940157/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.2.926
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