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Importance of thiols in the repair mechanisms of DNA containing AP (apurinic or apyrimidinic) sites.
Addition of thiol compounds containing an anionic group to the 3'-terminal unsaturated sugar of the 5' fragment obtained from an oligonucleotide containing an AP site cleaved by beta-elimination, can be followed by gel electrophoresis. The technique enables to distinguish between two mecha...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1988
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC338758/ https://ncbi.nlm.nih.gov/pubmed/3263620 |
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