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Importance of thiols in the repair mechanisms of DNA containing AP (apurinic or apyrimidinic) sites.

Addition of thiol compounds containing an anionic group to the 3'-terminal unsaturated sugar of the 5' fragment obtained from an oligonucleotide containing an AP site cleaved by beta-elimination, can be followed by gel electrophoresis. The technique enables to distinguish between two mecha...

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Bibliografiske detaljer
Main Authors: Bailly, V, Verly, W G
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC338758/
https://ncbi.nlm.nih.gov/pubmed/3263620
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