Mitotic Centromere-associated Kinesin (MCAK) Mediates Paclitaxel Resistance

Paclitaxel has powerful anticancer activity, but some tumors are inherently resistant to the drug, whereas others are initially sensitive but acquire resistance during treatment. To deal with this problem, it will be necessary to understand the mechanisms of drug action and resistance. Recent studie...

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Bibliografiske detaljer
Main Authors: Ganguly, Anutosh, Yang, Hailing, Pedroza, Mesias, Bhattacharya, Rajat, Cabral, Fernando
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196137/
https://ncbi.nlm.nih.gov/pubmed/21903575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.296483
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