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Mitotic Centromere-associated Kinesin (MCAK) Mediates Paclitaxel Resistance

Paclitaxel has powerful anticancer activity, but some tumors are inherently resistant to the drug, whereas others are initially sensitive but acquire resistance during treatment. To deal with this problem, it will be necessary to understand the mechanisms of drug action and resistance. Recent studie...

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Bibliografische gegevens
Hoofdauteurs: Ganguly, Anutosh, Yang, Hailing, Pedroza, Mesias, Bhattacharya, Rajat, Cabral, Fernando
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196137/
https://ncbi.nlm.nih.gov/pubmed/21903575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.296483
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