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Cell cycle dependent degradation of MCAK: evidence against a role in anaphase chromosome movement

MCAK, a kinesin related motor protein with microtubule depolymerizing activity, is known to play an important role in spindle assembly and correcting errors in mitotic chromosome alignment. Experiments to determine how cellular levels of the protein are regulated demonstrate that MCAK accumulates du...

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Bibliografische gegevens
Hoofdauteurs: Ganguly, Anutosh, Bhattacharya, Rajat, Cabral, Fernando
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677962/
https://ncbi.nlm.nih.gov/pubmed/18843200
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