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Cell cycle dependent degradation of MCAK: evidence against a role in anaphase chromosome movement

MCAK, a kinesin related motor protein with microtubule depolymerizing activity, is known to play an important role in spindle assembly and correcting errors in mitotic chromosome alignment. Experiments to determine how cellular levels of the protein are regulated demonstrate that MCAK accumulates du...

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Detalhes bibliográficos
Main Authors: Ganguly, Anutosh, Bhattacharya, Rajat, Cabral, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677962/
https://ncbi.nlm.nih.gov/pubmed/18843200
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