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Mitotic Centromere-associated Kinesin (MCAK) Mediates Paclitaxel Resistance

Paclitaxel has powerful anticancer activity, but some tumors are inherently resistant to the drug, whereas others are initially sensitive but acquire resistance during treatment. To deal with this problem, it will be necessary to understand the mechanisms of drug action and resistance. Recent studie...

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Bibliografske podrobnosti
Main Authors: Ganguly, Anutosh, Yang, Hailing, Pedroza, Mesias, Bhattacharya, Rajat, Cabral, Fernando
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196137/
https://ncbi.nlm.nih.gov/pubmed/21903575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.296483
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