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Mitotic Centromere-associated Kinesin (MCAK) Mediates Paclitaxel Resistance

Paclitaxel has powerful anticancer activity, but some tumors are inherently resistant to the drug, whereas others are initially sensitive but acquire resistance during treatment. To deal with this problem, it will be necessary to understand the mechanisms of drug action and resistance. Recent studie...

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Main Authors: Ganguly, Anutosh, Yang, Hailing, Pedroza, Mesias, Bhattacharya, Rajat, Cabral, Fernando
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196137/
https://ncbi.nlm.nih.gov/pubmed/21903575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.296483
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