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KIBRA Protein Phosphorylation Is Regulated by Mitotic Kinase Aurora and Protein Phosphatase 1

Recent genetic studies in Drosophila identified Kibra as a novel regulator of the Hippo pathway, which controls tissue growth and tumorigenesis by inhibiting cell proliferation and promoting apoptosis. The cellular function and regulation of human KIBRA remain largely unclear. Here, we show that KIB...

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Bibliographic Details
Main Authors: Xiao, Ling, Chen, Yuanhong, Ji, Ming, Volle, Deanna J., Lewis, Robert E., Tsai, Ming-Ying, Dong, Jixin
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196099/
https://ncbi.nlm.nih.gov/pubmed/21878642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246850
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