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KIBRA Regulates Aurora Kinase Activity and Is Required for Precise Chromosome Alignment During Mitosis

The Hippo pathway controls organ size and tumorigenesis by inhibiting cell proliferation and promoting apoptosis. KIBRA was recently identified as a novel regulator of the Hippo pathway. Several of the components of the Hippo pathway are important regulators of mitosis-related cell cycle events. We...

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Detalhes bibliográficos
Main Authors: Zhang, Lin, Iyer, Jyoti, Chowdhury, Aparajita, Ji, Ming, Xiao, Ling, Yang, Shuping, Chen, Yuanhong, Tsai, Ming-Ying, Dong, Jixin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464516/
https://ncbi.nlm.nih.gov/pubmed/22904328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.385518
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