KIBRA Protein Phosphorylation Is Regulated by Mitotic Kinase Aurora and Protein Phosphatase 1

Recent genetic studies in Drosophila identified Kibra as a novel regulator of the Hippo pathway, which controls tissue growth and tumorigenesis by inhibiting cell proliferation and promoting apoptosis. The cellular function and regulation of human KIBRA remain largely unclear. Here, we show that KIB...

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Bibliografische gegevens
Hoofdauteurs: Xiao, Ling, Chen, Yuanhong, Ji, Ming, Volle, Deanna J., Lewis, Robert E., Tsai, Ming-Ying, Dong, Jixin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2011
Onderwerpen:
Signal Transduction
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196099/
https://ncbi.nlm.nih.gov/pubmed/21878642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246850
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