KIBRA Protein Phosphorylation Is Regulated by Mitotic Kinase Aurora and Protein Phosphatase 1

Recent genetic studies in Drosophila identified Kibra as a novel regulator of the Hippo pathway, which controls tissue growth and tumorigenesis by inhibiting cell proliferation and promoting apoptosis. The cellular function and regulation of human KIBRA remain largely unclear. Here, we show that KIB...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Xiao, Ling, Chen, Yuanhong, Ji, Ming, Volle, Deanna J., Lewis, Robert E., Tsai, Ming-Ying, Dong, Jixin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2011
Pynciau:
Signal Transduction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196099/
https://ncbi.nlm.nih.gov/pubmed/21878642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246850
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