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KIBRA Regulates Hippo Signaling Activity via Interactions with Large Tumor Suppressor Kinases
The Hippo pathway controls tissue growth and tumorigenesis by inhibiting cell proliferation and promoting apoptosis. Recent genetic studies in Drosophila identified Kibra as a novel regulator of Hippo signaling. Human KIBRA has been associated with memory performance and cell migration. However, it...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048666/ https://ncbi.nlm.nih.gov/pubmed/21233212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.173468 |
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