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KIBRA Regulates Hippo Signaling Activity via Interactions with Large Tumor Suppressor Kinases

The Hippo pathway controls tissue growth and tumorigenesis by inhibiting cell proliferation and promoting apoptosis. Recent genetic studies in Drosophila identified Kibra as a novel regulator of Hippo signaling. Human KIBRA has been associated with memory performance and cell migration. However, it...

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Autors principals: Xiao, Ling, Chen, Yuanhong, Ji, Ming, Dong, Jixin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048666/
https://ncbi.nlm.nih.gov/pubmed/21233212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.173468
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