Genetic and Genomic Analyses of RNA Polymerase II-pausing Factor in Regulation of Mammalian Transcription and Cell Growth

Many mammalian genes are occupied by paused RNA polymerase II (pol II) in the promoter-proximal region on both sides of the transcription start site. However, the impact of pol II pausing on gene expression and cell biology is not fully understood. In this study, we used a Cre-Lox system to conditio...

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Main Authors: Sun, Jianlong, Pan, Haihui, Lei, Chengwei, Yuan, Bin, Nair, Sreejith J., April, Craig, Parameswaran, Balaji, Klotzle, Brandy, Fan, Jian-Bing, Ruan, Jianhua, Li, Rong
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Gene Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196092/
https://ncbi.nlm.nih.gov/pubmed/21865163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.269167
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