Genetic and Genomic Analyses of RNA Polymerase II-pausing Factor in Regulation of Mammalian Transcription and Cell Growth

Many mammalian genes are occupied by paused RNA polymerase II (pol II) in the promoter-proximal region on both sides of the transcription start site. However, the impact of pol II pausing on gene expression and cell biology is not fully understood. In this study, we used a Cre-Lox system to conditio...

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Detalhes bibliográficos
Main Authors: Sun, Jianlong, Pan, Haihui, Lei, Chengwei, Yuan, Bin, Nair, Sreejith J., April, Craig, Parameswaran, Balaji, Klotzle, Brandy, Fan, Jian-Bing, Ruan, Jianhua, Li, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196092/
https://ncbi.nlm.nih.gov/pubmed/21865163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.269167
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