Genetic and Genomic Analyses of RNA Polymerase II-pausing Factor in Regulation of Mammalian Transcription and Cell Growth

Many mammalian genes are occupied by paused RNA polymerase II (pol II) in the promoter-proximal region on both sides of the transcription start site. However, the impact of pol II pausing on gene expression and cell biology is not fully understood. In this study, we used a Cre-Lox system to conditio...

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Bibliografiske detaljer
Main Authors: Sun, Jianlong, Pan, Haihui, Lei, Chengwei, Yuan, Bin, Nair, Sreejith J., April, Craig, Parameswaran, Balaji, Klotzle, Brandy, Fan, Jian-Bing, Ruan, Jianhua, Li, Rong
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Gene Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196092/
https://ncbi.nlm.nih.gov/pubmed/21865163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.269167
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