Combined Treatment with the Mood Stabilizers Lithium and Valproate Produces Multiple Beneficial Effects in Transgenic Mouse Models of Huntington's Disease

Emerging evidence suggests that the mood stabilizers lithium and valproate (VPA) have broad neuroprotective and neurotrophic properties, and that these occur via inhibition of glycogen synthase kinase 3 (GSK-3) and histone deacetylases (HDACs), respectively. Huntington's disease (HD) is an inhe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chiu, Chi-Tso, Liu, Guangping, Leeds, Peter, Chuang, De-Maw
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194069/
https://ncbi.nlm.nih.gov/pubmed/21796107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.128
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados