The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain

Por Kim, Hyeon Ju, Leeds, Peter, Chuang, De-Maw
Publicado em 2009

Histone deacetylase inhibition alters histone methylation associated with heat shock protein 70 promoter modifications in astrocytes and neurons

Por Marinova, Zoya, Leng, Yan, Leeds, Peter, Chuang, De-Maw
Publicado em 2010

Combined Treatment with the Mood Stabilizers Lithium and Valproate Produces Multiple Beneficial Effects in Transgenic Mouse Models of Huntington's Disease

Por Chiu, Chi-Tso, Liu, Guangping, Leeds, Peter, Chuang, De-Maw
Publicado em 2011

The Mood Stabilizers Valproic Acid and Lithium Enhance Mesenchymal Stem Cell Migration via Distinct Mechanisms

Por Tsai, Li-Kai, Leng, Yan, Wang, Zhifei, Leeds, Peter, Chuang, De-Maw
Publicado em 2010

Valproic acid attenuates blood–brain barrier disruption in a rat model of transient focal cerebral ischemia: the roles of HDAC and MMP-9 inhibition

Por Wang, Zhifei, Leng, Yan, Tsai, Li-Kai, Leeds, Peter, Chuang, De-Maw
Publicado em 2011

Mesenchymal Stem Cells Primed With Valproate and Lithium Robustly Migrate to Infarcted Regions and Facilitate Recovery in a Stroke Model

Por Tsai, Li-Kai, Wang, Zhifei, Munasinghe, Jeeva, Leng, Yan, Leeds, Peter, Chuang, De-Maw
Publicado em 2011

Synergistic Neuroprotective Effects of Lithium and Valproic Acid or Other Histone Deacetylase Inhibitors in Neurons: Roles of Glycogen Synthase Kinase-3 Inhibition

Por Leng, Yan, Liang, Min-Huei, Ren, Ming, Marinova, Zoya, Leeds, Peter, Chuang, De-Maw
Publicado no J Neurosci (2008)

Valproic Acid and Other HDAC Inhibitors Upregulate FGF21 Gene Expression and Promote Process Elongation in Glia by Inhibiting HDAC2 and 3

Por Leng, Yan, Wang, Junyu, Wang, Zhifei, Liao, Hsiao-Mei, Wei, Monica, Leeds, Peter, Chuang, De-Maw
Publicado no Int J Neuropsychopharmacol (2016)

Posttrauma cotreatment with lithium and valproate: reduction of lesion volume, attenuation of blood-brain barrier disruption, and improvement in motor coordination in mice with tra...

Por Yu, Fengshan, Wang, Zhifei, Tanaka, Mikiei, Chiu, Chi-Tso, Leeds, Peter, Zhang, Yumin, Chuang, De-Maw
Publicado no J Neurosurg (2013)

FGF-21, a novel metabolic regulator, has a robust neuroprotective role and is dramatically elevated in neurons by mood stabilizers

Por Leng, Yan, Wang, Zhifei, Tsai, Li-Kai, Leeds, Peter, Fessler, Emily Bame, Wang, Junyu, Chuang, De-Maw
Publicado em 2014

Tubastatin A, an HDAC6 inhibitor, alleviates stroke-induced brain infarction and functional deficits: potential roles of α-tubulin acetylation and FGF-21 up-regulation

Por Wang, Zhifei, Leng, Yan, Wang, Junyu, Liao, Hsiao-Mei, Bergman, Joel, Leeds, Peter, Kozikowski, Alan, Chuang, De-Maw
Publicado no Sci Rep (2016)

Valproic acid induces functional heat shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation

Por Marinova, Zoya, Ren, Ming, Wendland, Jens R., Leng, Yan, Liang, Min-Huei, Yasuda, Shigeru, Leeds, Peter, Chuang, De-Maw
Publicado em 2009

Chronic Valproate Treatment Enhances Post-ischemic Angiogenesis and Promotes Functional Recovery in a Rat Model of Ischemic Stroke

Por Wang, Zhifei, Tsai, Li-Kai, Munasinghe, Jeeva, Leng, Yan, Fessler, Emily Bame, Chibane, Fairouz, Leeds, Peter, Chuang, De-Maw
Publicado em 2012

Lentivirally mediated GSK-3β silencing in the hippocampal dentate gyrus induces antidepressant-like effects in stressed mice

Por Omata, Naoto, Chiu, Chi-Tso, Moya, Pablo R., Leng, Yan, Wang, Zhifei, Hunsberger, Joshua G., Leeds, Peter, Chuang, De-Maw
Publicado em 2010

A New Avenue for Lithium: Intervention in Traumatic Brain Injury

Por Leeds, Peter R., Yu, Fengshan, Wang, Zhifei, Chiu, Chi-Tso, Zhang, Yumin, Leng, Yan, Linares, Gabriel R., Chuang, De-Maw
Publicado em 2014