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Lentivirally mediated GSK-3β silencing in the hippocampal dentate gyrus induces antidepressant-like effects in stressed mice
Inhibition of glycogen synthase kinase-3 (GSK-3) by pharmacological tools can produce antidepressant-like effects in rodents. However, the GSK-3 isoform(s) and brain region(s) involved in regulating these behavioral effects remain elusive. We studied the effects of bilateral intra-hippocampal inject...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3125712/ https://ncbi.nlm.nih.gov/pubmed/20604988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1461145710000726 |
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