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Valproic acid induces functional heat shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation

Neuroprotective properties of the mood stabilizer valproic acid (VPA) are implicated in its therapeutic efficacy. Heat shock protein 70 (HSP70) is a molecular chaperone, neuroprotective and anti-inflammatory agent. The present study aimed to investigate underlying mechanisms and functional significa...

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Detalhes bibliográficos
Main Authors: Marinova, Zoya, Ren, Ming, Wendland, Jens R., Leng, Yan, Liang, Min-Huei, Yasuda, Shigeru, Leeds, Peter, Chuang, De-Maw
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766424/
https://ncbi.nlm.nih.gov/pubmed/19765194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06385.x
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