The Mood Stabilizer Lithium Potentiates the Antidepressant-Like Effects and Ameliorates Oxidative Stress Induced by Acute Ketamine in a Mouse Model of Stress

BACKGROUND: Evidence suggests that mammalian target of rapamycin activation mediates ketamine’s rapid but transient antidepressant effects and that glycogen synthase kinase-3β inhibits this pathway. However, ketamine has associated psychotomimetic effects and a high risk of abuse. The mood stabilize...

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Publicat a:Int J Neuropsychopharmacol
Autors principals: Chiu, Chi-Tso, Scheuing, Lisa, Liu, Guangping, Liao, Hsiao-Mei, Linares, Gabriel R., Lin, Dora, Chuang, De-Maw
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438544/
https://ncbi.nlm.nih.gov/pubmed/25548109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyu102
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