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Preclinical and Clinical Investigations of Mood Stabilizers for Huntington's Disease: What Have We Learned?
Huntington's disease (HD) is a lethal, autosomal dominant neurodegenerative disorder caused by CAG repeat expansions at exon 1 of the huntingtin (Htt) gene, which encodes for a mutant huntingtin protein (mHtt). Prominent symptoms of HD include motor dysfunction, characterized by chorea; psychia...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ivyspring International Publisher
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183923/ https://ncbi.nlm.nih.gov/pubmed/25285035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.9898 |
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