Preclinical and Clinical Investigations of Mood Stabilizers for Huntington's Disease: What Have We Learned?

Huntington's disease (HD) is a lethal, autosomal dominant neurodegenerative disorder caused by CAG repeat expansions at exon 1 of the huntingtin (Htt) gene, which encodes for a mutant huntingtin protein (mHtt). Prominent symptoms of HD include motor dysfunction, characterized by chorea; psychia...

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Bibliografiske detaljer
Main Authors: Scheuing, Lisa, Chiu, Chi-Tso, Liao, Hsiao-Mei, Linares, Gabriel R., Chuang, De-Maw
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2014
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183923/
https://ncbi.nlm.nih.gov/pubmed/25285035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.9898
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