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Two oppositely-oriented arrays of low affinity recognition sites in oriC guide progressive binding of DnaA during E. coli pre-RC assembly

The onset of chromosomal DNA replication requires highly precise and reproducible interactions between initiator proteins and replication origins to assemble a pre-replicative complex (pre-RC) that unwinds the DNA duplex. In bacteria, initiator protein DnaA, bound to specific high and low affinity r...

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Библиографические подробности
Главные авторы: Rozgaja, Tania A., Grimwade, Julia E., Iqbal, Maryam, Czerwonka, Christopher, Vora, Mansi, Leonard, Alan C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192301/
https://ncbi.nlm.nih.gov/pubmed/21895796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2011.07827.x
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