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Low Affinity DnaA-ATP Recognition Sites in E. coli oriC Make Non-equivalent and Growth Rate-Dependent Contributions to the Regulated Timing of Chromosome Replication

Although the mechanisms that precisely time initiation of chromosome replication in bacteria remain unclear, most clock models are based on accumulation of the active initiator protein, DnaA-ATP. During each cell division cycle, sufficient DnaA-ATP must become available to interact with a distinct s...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Rao, Prassanna, Rozgaja, Tania A., Alqahtani, Abdulaziz, Grimwade, Julia E., Leonard, Alan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070618/
https://ncbi.nlm.nih.gov/pubmed/30093890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01673
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