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Building the bacterial orisome: high affinity DnaA recognition plays a role in setting the conformation of oriC DNA
During assembly of the E. coli pre-replicative complex (pre-RC), initiator DnaA oligomers are nucleated from three widely separated high affinity DnaA recognition sites in oriC. Oligomer assembly is then guided by low affinity DnaA recognition sites, but is also regulated by a switch-like conformati...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992943/ https://ncbi.nlm.nih.gov/pubmed/24443848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12525 |
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