SeqA blocking of DnaA-oriC interactions ensures staged assembly of the E. coli pre-RC

DnaA occupies only the three highest affinity binding sites in E. coli oriC throughout most of the cell cycle. Immediately prior to initiation of chromosome replication, DnaA interacts with additional recognition sites, resulting in localized DNA strand separation. These two DnaA/oriC complexes form...

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Main Authors: Nievera, Christian, Torgue, Julien J-C., Grimwade, Julia E., Leonard, Alan C.
格式: Artigo
語言:Inglês
出版: 2006
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1939805/
https://ncbi.nlm.nih.gov/pubmed/17114060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.09.016
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