SeqA blocking of DnaA-oriC interactions ensures staged assembly of the E. coli pre-RC

DnaA occupies only the three highest affinity binding sites in E. coli oriC throughout most of the cell cycle. Immediately prior to initiation of chromosome replication, DnaA interacts with additional recognition sites, resulting in localized DNA strand separation. These two DnaA/oriC complexes form...

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Hlavní autoři: Nievera, Christian, Torgue, Julien J-C., Grimwade, Julia E., Leonard, Alan C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1939805/
https://ncbi.nlm.nih.gov/pubmed/17114060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.09.016
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