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Mutational analysis reveals E. coli oriC interacts with both DnaA-ATP and DnaA-ADP during pre-RC assembly
Prior to initiating DNA synthesis, E. coli oriC switches from ORC, comprising initiator DnaA bound at three high affinity sites, to pre-RC, when additional DnaA molecules interact with low affinity sites. Two types of low affinity sites exist; R boxes that bind DnaA-ATP and DnaA-ADP with equal affin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2391298/ https://ncbi.nlm.nih.gov/pubmed/17850252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2007.05930.x |
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