Low Affinity DnaA-ATP Recognition Sites in E. coli oriC Make Non-equivalent and Growth Rate-Dependent Contributions to the Regulated Timing of Chromosome Replication

Although the mechanisms that precisely time initiation of chromosome replication in bacteria remain unclear, most clock models are based on accumulation of the active initiator protein, DnaA-ATP. During each cell division cycle, sufficient DnaA-ATP must become available to interact with a distinct s...

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Bibliografiska uppgifter
I publikationen:Front Microbiol
Huvudupphovsmän: Rao, Prassanna, Rozgaja, Tania A., Alqahtani, Abdulaziz, Grimwade, Julia E., Leonard, Alan C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2018
Ämnen:
Microbiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070618/
https://ncbi.nlm.nih.gov/pubmed/30093890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01673
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