लोड हो रहा है...

Antagonism of the Stat3–Stat3 Protein Dimer with Salicylic Acid Based Small Molecules

More than 50 new inhibitors of the oncogenic Stat3 protein were identified through a structure–activity relationship (SAR) study based on the previously identified inhibitor S3I-201 (IC(50) = 86 µm, K(i) > 300 µm). A key structural feature of these inhibitors is a salicylic acid moiety, which, by...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Fletcher, Steven, Page, Brent D. G., Zhang, Xialoei, Yue, Peibin, Li, Zhi Hua, Sharmeen, Sumaiya, Singh, Jagdeep, Zhao, Wei, Schimmer, Aaron D., Trudel, Suzanne, Turkson, James, Gunning, Patrick T.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192013/
https://ncbi.nlm.nih.gov/pubmed/21618433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201100194
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!