Design, Synthesis and in vitro Characterization of Novel Hybrid Peptidomimetic Inhibitors of STAT3 Protein

Aberrant activation of oncogenic signal transducer and activator of transcription 3 (STAT3) protein signaling pathways has been extensively implicated in human cancers. Given STAT3’s prominent dysregulatory role in malignant transformation and tumorigenesis, there has been a significant effort to di...

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Hlavní autoři: Shahani, Vijay M., Yue, Peibin, Fletcher, Steven, Sharmeen, Sumaiya, Sukhai, Mahadeo A., Luu, Diana P., Zhang, Xiaolei, Sun, Hong, Zhao, Wei, Schimmer, Aaron D., Turkson, James, Gunning, Patrick T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151534/
https://ncbi.nlm.nih.gov/pubmed/21216604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.12.010
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