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Rapid, General Access to Chiral β-Fluoroamines and β, β-Difluoroamines via Organocatalysis

[Image: see text] A rapid, general route to enantiopure β-fluoroamines and β,β-difluoroamines has been developed employing organocatalysis in both a two-pot and a one-pot procedure. Both chemical yields (64–82%) and enantioselectivity (94–98% ee) were excellent and represent a significant improvemen...

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Main Authors: Fadeyi, Olugbeminiyi O., Lindsley, Craig W.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192010/
https://ncbi.nlm.nih.gov/pubmed/19159275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol802930q
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